Amoxicillin Sodium

CAS No. 34642-77-8

Amoxicillin Sodium( Amoxicillin sodium | Lamoxy | Penamox )

Catalog No. M18459 CAS No. 34642-77-8

Amoxicillin Sodium is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Amoxicillin Sodium
  • Note
    Research use only, not for human use.
  • Brief Description
    Amoxicillin Sodium is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.
  • Description
    Amoxicillin sodium is a broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.
  • In Vitro
    Amoxicillin (Amoxycillin) sodium (1-100 μM; 24 hours; L. acidophilus) decreases living cells and increases degree of cell wall rupture in a dose-dependent manner.
  • In Vivo
    Amoxicillin (Amoxycillin) sodium (7 mg/kg; i.h.; female ICR/Swiss mice) inhibits strain numbers and improves the survival rate of rats in 1 mg/L or less.Amoxicillin (Amoxycillin) sodium (1.6-9.5 mg/kg; p.o.; daily, for 7 or 14 days; swiss albino mice) has against infection with chlamydia trachomatis in mice. Animal Model:Female ICR/Swiss mice Dosage:7 mg/kg Administration:Subcutaneous injection; every 8 h, for 24 hours Result:Inhibited bacterial numbers in a dose-dependent manner.Animal Model:Female ICR/Swiss mice Dosage:7 mg/kg Administration:Subcutaneous injection; every 8 h, for 4 days Result:Survived all animals that were infected with organisms for which MICs were 1 mg/L or less, and with the two strains for which MICs were 2 mg/L, 20 to 40% mortality.Animal Model:Swiss albino mice Dosage:1.6 and 9.5 mg/kg Administration:Oral administration; daily, for 7 or 14 days Result:Improved the activity of Chlamydia trachomatis infection in mice.
  • Synonyms
    Amoxicillin sodium | Lamoxy | Penamox
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    34642-77-8
  • Formula Weight
    387.39
  • Molecular Formula
    C16H18N3O5S·Na
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 39 mg/mL; 100.41 mM
  • SMILES
    [Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=C(O)C=C1)C([O-])=O
  • Chemical Name
    sodium (2S,5R,6R)-6-(2-amino-2-(4-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bystrzycka W, et al.Cent Eur J Immunol. 2016;41(1):1-5.
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